Projectes finançats o convenis de transferència de coneixement en actiu durant els últims quatre anys: 

• Projecte FIS PI17/00597

Títol: "La oxigenoterapia de alto flujo como adyuvante en el tratamiento de la sepsis grave. Ensayo clínico"
Durada: 2018-2020
Pressupost concedit: 36.905€

• Projecte Marató TV3 2021

Títol: "Impacte i seqüeles derivades de l'impuls resiratori elevat en els malalts crítics COVID-19 que requereixen ventilació mecànica: caracterització mecanística i genòmica mitjançant l'ús d'intel·ligència artificial"
Durada: 2021-2022
Pressupost concedit: 60.000€

• Minimizing asynchronies in mechanical ventilation: Current and future trends
  Autors: Subirà C, de Haro C, Magrans R, Fernández R, Blanch L. 
  Publicat a: Respir Care 2018, 63 (4): 464-478 http://dx.doi.org/10.4187/respcare.05949 PMID: 29487094
  
  
• Limitation of life support techniques at admission to the intensive care unit: a multicenter prospective cohort study
  Autors: Rubio O, Arnau A, Cano S, Subirà C, Balerdi B, Perea ME, Fernández-Vivas M, Barber M, Llamas N, Altaba S, Prieto A, Gómez V, Martin M, Paz M, Quesada B, Español V, Montejo JC, Gomez JM, Miro G, Xirgú J, Ortega A, Rascado P, Sánchez JM, Marcos A, Tizon A, Monedero P, Zabala E, Murcia C, Torrejon I, Planas K, Añon JM, Hernandez G, Fernandez MD, Guía C, Arauzo V, Perez JM, Catalan R, Gonzalez J, Poyo R, Tomas R, Saralegui I, Mancebo J, Sprung C, Fernández R. 
  Publicat a: J Intensive Care. 2018 Apr 13;6:24. doi: http://dx.doi.org/10.1186/s40560-018-0283-y PMID: 29686878
  
  
• Asynchronies in the Intensive Care Unit (ASYNICU) Group. Double Cycling During Mechanical Ventilation: Frequency, Mechanisms, and Physiologic Implications
  Autors: de Haro C, López-Aguilar J, Magrans R, Montanya J, Fernández-Gonzalo S, Turon M, Gomà G, Chacón E, Albaiceta GM, Fernández R, Subirà C, Lucangelo U, Murias G, Rué M, Kacmarek RM, Blanch L
  Publicat a: Crit Care Med. 2018; 46(9):1385-1392. http://dx.doi.org/10.1097/CCM.0000000000003256 PMID: 29985211
  
  
• Noninvasive ventilation for respiratory failure: a note of caution in selected patients
  Autors: Macharete C, Ventura L, Rubio O, Catalan I, Cano S, Alcoverro JM, Subira C, Masclans J, Rognoni G, Fernandez R.
  Publicat a: Intensive Care Med. 2018; 44(9): 1586-1587. doi: http://dx.doi.org/10.1007/s00134-018-5275-9 PMID: 29934923
  
  
• High red blood cell distribution width as a marker of hospital mortality after ICU discharge: a cohort study
  Autors: Fernandez R, Cano S, Catalan I, Rubio O, Subira C, Masclans J, Rognoni G, Ventura L, Macharete C, Winfield L, Alcoverro JM.
  Publicat a: J Intensive Care 2018; 6: 74 https://doi.org/10.1186/s40560-018-0343-3 PMID: 30473793
  
  
• Predicting patient-ventilator asynchronies with hidden Markov models
  Autors: Marchuk Y, Magrans R, Sales B, Montanya J, López-Aguilar J, de Haro C, Gomà G, Subirà C, Fernández R, Kacmarek RM, Blanch Ll. .
  Publicat a: Sci Rep. 2018 Dec 4;8(1):17614. https://doi.org/10.1038/s41598-018-36011-0 PMID: 30514876
  
  
• Impaired cerebral autoregulation is associated with brain dysfunction in septic patients
  Autors: Crippa IA, Subira C, Vincent JL, Fernandez R, Cano S, Zama F, Creteur J, Taccone FS.
  Publicat a: Critical Care 2018; 22:327 https://doi.org/10.1186/s13054-018-2258-8 PMID: 30514349
  
  
• Clinical characteristics, evolution, and treatment-related risk factors for mortality among immunosuppressed patients with influenza A (H1N1) virus admitted to the intensive care unit
  Autors: Garnacho-Montero J, León-Moya C, Gutiérrez-Pizarraya A, on Behalf GETGAG Study Group (Dr I. Catalan).
  Publicat a: J Crit Care. 2018 Dec;48:172-177. PMID: 30216935
  
  
• Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study
  Autors: Moreno G, Rodríguez A, Reyes LF, GETGAG Study Group (Dr I.Catalan).
  Publicat a: Intensive Care Med. 2018 Sep;44(9):1470-1482. PMID: 30074052
  
  
• Patients with influenza A (H1N1)pdm09 admitted to the ICU. Impact of the recommendations of the SEMICYUC
  Autors: Marin-Corral J, Climent C, Muñoz R, GETGAG SEMICYUC. (Dr I. Catalan)
  Publicat a: Med Intensiva. 2018 Nov;42(8):473-481. PMID: 29559173
  
  
• Relationship between acute kidney injury and serum procalcitonin (PCT) concentration in critically ill patients with influenza infection
  Autors: Rodríguez A, Reyes LF, Monclou J on behalf GETGAG study group (Dr I. Catalan)
  Publicat a: Med Intensiva. 2018 Oct;42(7):399-408. PMID: 29433841
  
  
• Effect of pressure support vs T-piece ventilation strategies during spontaneous breathing trials on successful extubation among patients receiving mechanical ventilation: a randomized clinical trial
  Autors: Subirà C, Hernández G, Vázquez A, Rodríguez-García R, González-Castro A, García C, Rubio O, Ventura L, López A, de la Torre MC, Keough E, Arauzo V, Hermosa C, Sánchez C, Tizón A, Tenza E, Laborda C, Cabañes S, Lacueva V, Fernández MM, Arnau A, Fernández R.
  Publicat a: JAMA 2019; 321(22): 2175-2182. https://doi.org/10.1001/jama.2019.7234 PMID: 31184740
  
  
• Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
  Autors: de Haro C, Magrans R, López-Aguilar J, Montanyà J, Lena E, Subirà C, Fernandez-Gonzalo S, Gomà G, Fernández R, Albaiceta GM, Skrobik Y, Lucangelo U, Murias G, Ochagavia A, Kacmarek RM, Rue M, Blanch L; Asynchronies in the Intensive Care Unit (ASYNICU) Group.
  Publicat a: Crit Care. 2019 Jul 5;23(1):245. https://doi.org/10.1186/s13054-019-2531-5 . PMID: 31277722
  
  
• Proportional Assist Ventilation feasibility in the early stage of respiratory failure: a prospective randomized multicenter trial
  Autors: Delgado M, Subirá C, Hermosa C, Gordo F, Riera J, Fernández R.
  Publicat a: Minerva Anestesiol. 2019 Aug;85(8):862-870. https://doi.org/10.23736/S0375-9393.19.12618-1 PMID: 30735015
  
  
• Asynchronies in the Intensive Care Unit (ASYNICU) Group. Patient-ventilator asynchronies during mechanical ventilation: current knowledge and research priorities
  Autors: de Haro C, Ochagavia A, López-Aguilar J, Fernandez-Gonzalo S, Navarra-Ventura G, Magrans R, Montanyà J, Blanch L
  Publicat a: Intensive Care Med Exp. 2019 Jul 25;7(Suppl 1):43. https://doi.org/10.1186/s40635-019-0234-5 Review. PMID: 31346799
  
  
• Sound isolation and music on the comfort of mechanically ventilated critical patients
  Autors: Mateu-Capell M, Arnau A, Juvinya D, Montesinos J, Fernandez R.
  Publicat a: Nurs Crit Care. 2019 Sep;24(5):290-298 https://doi.org/10.1111/nicc.12407 PMID: 30592127
  
  
• ¿Se debe restringir el ingreso en cuidados intensivos solo a los pacientes más graves?
  Autors: Fernandez R, Alcoverro JM, Catalán I, Rubio O, Cano S, Subirà
  Publicat a: C  Med Intensiva. 2019 Aug - Sep;43(6):382-384. http://dx.doi.org/10.1016/j.medin.2017.09.002 PMID: 29055516
  
  
• ¿Resulta útil evaluar la fragilidad de los pacientes al ingreso en la unidad de cuidados intensivos (UCI)?
  Autors: Rubio O, Fernández R. 
  Publicat a: Med Intensiva 2019; Oct 43 (7) 393-394 http://dx.doi.org/10.1016/j.medin.2019.04.007
  
  
• Severity scores should incorporate limitations on life support for predicting mortality
  Autors: Fernandez R, Ventura L, Macharete C, Catalan I, Cano S, Alcoverro JM, Subira C, Masclans J, Rognoni G, Rubio O.
  Publicat a: Med Intensiva 2019 Nov; 43(8): 509-510. http://dx.doi.org/10.1016/j.medin.2018.09.007 PMID: 30482559
  
  
• Development and validation of a sample entropy-based method to identify complex patient-ventilator interactions during mechanical ventilation
  Autors: Sarlabous L, Aquino‑Esperanza J, Magrans R, de Haro C, López‑Aguilar J, Subirà C, Batlle M, Rué M, Gomà G, Ochagavia A, Fernández R, Blanch L.
  Publicat a: Sci Rep. 2020 Aug 17; 10(1):13911. http://dx.doi.org/10.1038/s41598-020-70814-4 PMID: 32807815
  
  
• Cognitive phenotypes 1 month after ICU discharge in mechanically ventilated patients: a prospective observational cohort study
  Autors: Fernández-Gonzalo S, Navarra-Ventura G, Bacardit N, Gomà Fernández G, de Haro C, Subirà C, López-Aguilar J, Magrans R, Sarlabous L, Aquino Esperanza J, Jodar M, Rué M, Ochagavía A, Palao DJ, Fernández R, Blanch L.
  Publicat a: Crit Care. 2020 Oct 21; 24(1):618. http://dx.doi.org/10.1186/s13054-020-03334-2 PMID: 33087171
  
  
• Double and multiple cycling in mechanical ventilation: Complex events with varying clinical effects
  Autors: Aquino Esperanza J, Sarlabous L, de Haro C, Batlle M, Magrans R, Lopez-Aguilar J, Fernandez R, Blanch L.
  Publicat a: Med Intensiva 2020; 44: 449-51. http://dx.doi.org/10.1016/j.medin.2019.06.004 PMID: 31337498
  
  
• An effective pressure-flow characterization of respiratory asynchronies in mechanical ventilation
  Autors: Casagrande A, Quintavalle F, Fernandez R, Blanch L, Ferluga M, Lena E, Fabris F, Lucangelo U.
  Publicat a: J Clin Monit Comput. 2021 Apr;35(2):289-296. https://doi.org/10.1007/s10877-020-00469-z PMID: 31993892
  
  
• Longitudinal Changes in Patient-Ventilator Asynchronies and Respiratory System Mechanics Before and After Tracheostomy
  Autors: Lena E, Aquino-Esperanza J, López-Aguilar J, Magrans R, de Haro C, Sarlabous L, López N, Montanyà J, Rué M, Kacmarek RM, Lucangelo U, Fernández R, et al.
  Publicat a: Respir Care 2021 Sep;66(9):1389-1397. https://doi.org/10.4187/respcare.08824 PMID: 34230215
  
  
• Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
  Autors: Armañac-Julián P, Hernando D, Lázaro J, de Haro C, Magrans R, Morales J, Moeyersons J, Sarlabous L, López-Aguilar J, Subirà C, Fernández R, Orini M, Laguna P, Varon C, Gil E, Bailón R, Blanch L.
  Publicat a: Sci Rep. 2021 Aug 6;11(1):16014. https://doi.org/10.1038/s41598-021-95282-2 PMID: 34362950
  
  
• The ventilated brain: the central nervous system during lung injury and mechanical ventilation
  Autors: Albaiceta GM, Brochard L, Dos Santos C, Fernández R, Georgopoulos D, Girard T, Jubran A, López-Aguilar J, Mancebo J, Pelosi P, Skrobik Y, Thille AW, Wilcox ME, Blanch Ll.
  Publicat a: Br J Anaesth. 2021 Jul 30:S0007-0912(21)00434-7. doi: 10.1016/j.bja.2021.05.038. Online ahead of print. PMID: 34340836
  
  
• Predicción de ingreso hospitalario en los pacientes con bajo nivel de prioridad de triaje atendidos en un servicio de urgencias
  Autors: Leey C, Zorrilla J; Arnau A; Jaen L, Lladó D; Genè E.
  Publicat a: Emergencias 2020; 32 : 395 - 402
  
  
• Análisis de la demanda de atención urgente en un municipio de la Cataluña central. Atención Primaria 2020
  Autors: Ruiz-Comellas A; Zorrilla JG; Fusté M; Mendioroz J.
  Publicat a: Elsevier, 01/06/2020. ISSN 0212-6567
  
  
• Características de la ventilación no invasiva prolongada en los servicios de urgencias hospitalarios y su impacto en la eficacia. Análisis del registro VNICat
  Autors: Arranz M, Jacob J, Sancho-Ramoneda M; Lopez A, Navarro-Saez M, Cousiño JR, Lopez-Altimiras X, Lopez F, Garcia-trallero O, German A, Farré J, Zorrilla J.
  Publicat a: Med Intensiva 2020. Doi.org/10.1016/j.medin.2020.02.007
  
  
• Estudio SephCat: Análisis de los servicios de emergencias prehospitalarios en Cataluña
  Autors: Escalada X; Sanchez P; Hernández R; Gené E; Jacob J; Alonso G; Rimabau P; Zorrilla J; Casarramona F; Netto C; Flores S; Puig M; Villamor A; Sánchez M; Miró O.
  Publicat a: Emergencias 2020; 32 : 90 - 96
  
  
• Work shift in the hospitals’ emergency departments: the Spanish experience
  Autor: Zorrilla J.
  Publicat a: Eur J Emerg Med 2019; 26: 394 - 395
  
  
• Análisis del uso de la ecografía a pie de cama en los servcios de urgencias hospitalarios de Cataluña: estudio Ecurcat
  Autors: Jacob J; Zorrilla J; Gené E; et al.
  Publicat a: Anales del Sistema Sanitario de Navarra 2018; 41: 161 - 169
  
  
• Ventilación no invasiva en los servicios de urgencias hospitalarios publicos de Cataluña. Estudio Venur-Cat
  Autors: Jacob J; Zorrilla J; Gené E; et al.
  Publicat a: Med Intensiva 2018; 42: 141-150
  
  
• Estudio SuhCat-5: comparación de la percepción de la calidad de los servicios de urgencias en Cataluña entre los profesionales sanitarios y sus responsables
  Autors: Jacob J; Gené E; Alonso G; Rimbau P; Zorrilla J; et al.
  Publicat a: Emergencias 2018; 30: 45 - 49
  
  
• Nasal flaring as a clinical sign of respiratory acidosis in patients with dyspnea
  Autors: Zorrilla JG, Arnau A, Rafat R, Garcia D, Mas A, Fernandez R.
  Publicat a: Am J Emerg Med 2017 35: 548-553. doi: 10.1016/j.ajem.2016.12.008 PMID: 28007319
  
  
• The Effect of Clusters of Double Triggering and Ineffective Efforts in Critically Ill Patients
  Autors: Magrans R, Ferreira F, Sarlabous L, López-Aguilar J, Gomà G, Fernandez-Gonzalo S, Navarra-Ventura G, Fernández R, et al.
  Publicat a: Crit Care Med. 2022 Feb 7. doi: 10.1097/CCM.0000000000005471. Online ahead of print. PMID: 35120043
  
  
• Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study
  Autors: Wendel-Garcia PD, Mas A, González-Isern C, Ferrer R, Máñez R, Masclans JR, Sandoval E, Vera P, Trenado J, Fernández R, , et al.
  Publicat a: Crit Care. 2022 Feb 8;26(1):37. doi: 10.1186/s13054-022-03905-5. PMID: 35135588
  
  
• Mechanical ventilation in Spain, 1998-2016: Epidemiology and outcomes
  Autors: Peñuelas O, Frutos-Vivar F, Muriel A, Mancebo J, García-Jiménez A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A.
  Publicat a: Med Intensiva 2021; 45 (1): 3-13 http://dx.doi.org/10.1016/j.medin.2020.04.024 PMID: 32723483
  
  
• Soporte ventilatorio no invasivo en pacientes con neumonía por Covid19: un registro multicentrico español
  Autors: Fernandez R, Gonzalez de Molina FJ, Batlle M, Fernandez MM, Hernandez S, Villagra A y Grupo Semicriticos Covid.
  Publicat a: Med Intensiva 2021; 45 (5): 315-317. http://dx.doi.org/10.1016/j.medin.2021.02.002 PMID: 33722421
  
  
• Mechanical ventilation in Spain, 1998-2016: changes in the disconnection of mechanical ventilation
  Autors: Frutos-Vivar F, Peñuelas O, Muriel A, Mancebo J, García-Jiménez A, de Pablo R, Valledor M, Ferrer M, León M, Quiroga JM, Temprano S, Vallverdú I, Fernández R, Gordo F, Anzueto A, Esteban A.
  Publicat a: Med Intensiva (Engl Ed). 2021 Jun 4:S0210-5691(21)00079-6. http://dx.doi.org/10.1016/j.medin.2021.04.005 Online ahead of print. PMID: 34092422
  
  
• High-flow oxygen to prevent postextubation respiratory failure in high-risk nonhypercapnic patients: a randomized multicenter trial
  Autors: Fernandez R, Subira C, Frutos-Vivar F, Rialp G, Laborda C, Masclans JR, Lesmes A, Panadero L, Hernandez G.
  Publicat a: Ann Intensive Care 2017; 7: 47. http://dx.doi.org/10.1186/s13613-017-0270-9
  
  
• Reconnection to mechanical ventilation for 1 h after a successful spontaneous breathing trial reduces reintubation in critically ill patients: a multicenter randomized controlled trial
  Autors: Fernandez MM, González-Castro A, Magret M, Bouza MT, Ibañez M, García C, Balerdi B, Mas A, Arauzo V, Añón JM, Ruiz F, Ferreres J, Tomás R, Alabert M, Tizón AI, Altaba S, Llamas N, Fernandez R.
  Publicat a: Intensive Care Med. 2017; 43 (11): 1660-1667. http://dx.doi.org/10.1007/s00134-017-4911-0 PMID: 28936675
  
  
• ADENI-UCI study: Analysis of non-income decisions in ICU as a measure of limitation of life support treatments
  Autors: Escudero-Acha P, Leizaola O, Lázaro N, Cordero M, Cossío AM, Ballesteros D, Recena P, Tizón AI, Palomo M, Del Campo MM, Freita S, Duerto J, Bilbao NM, Vidal B, González-Romero D, Diaz-Dominguez F, Revuelto J, Blasco ML, Domezain M, de la Concepción Pavía-Pesquera M, Rubio O, et al.
  Publicat a: Med Intensiva (Engl Ed). 2022 Feb 26:S2173-5727(22)00034-0. doi: 10.1016/j.medine.2022.02.008. Online ahead of print. PMID: 35227639
  
  
• Detection of frailty and palliative needs from discharged critical care patients in collaboration with primary care
  Autors: Ferré C, Canelles S, Daniel X, Rubio O, Esteban F, Pobo A.
  Publicat a: Med Intensiva (Engl Ed). 2022 Feb;46(2):101-103. doi: 10.1016/j.medine.2021.11.018. PMID: 34863667
  
  
• Ethical recommendations for a difficult decision-making in intensive care units due to the exceptional situation of crisis by the COVID-19 pandemia: A rapid review & consensus of experts
  Autors: Rubio O, Estella A, Cabre L, Saralegui-Reta I, Martin MC, Zapata L, Esquerda M, Ferrer R, Castellanos A, Trenado J, Amblas J.
  Publicat: Med Intensiva (Engl Ed). 2020 Oct;44(7):439-445. doi: 10.1016/j.medin.2020.04.006. PMID: 32402532
  
  
• Cerebral Autoregulation Indices Are Not Interchangeable in Patients With Sepsis
  Autors: Caldas J, Quispe-Cornejo AA, Crippa IA, Subira C, Creteur J, Panerai R, Taccone FS.
  Publicat a: Front. Neurol., 07 March 2022 | https://doi.org/10.3389/fneur.2022.760293